SUN-348 Risk Factors for the Development of BK Virus Infection in Kidney Transplant Recipients in Gilan Province During 2007-2015

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BK Virus in Kidney Transplant Recipients: The Influence of Immunosuppression

The incidence of BK virus infection in kidney transplant recipients has increased over recent decades, coincident with the use of more potent immunosuppression. More importantly, posttransplant BK virus replication has emerged as an important cause of graft damage and subsequent graft loss. Immunosuppression has been accepted as a major risk for BK virus replication. However, the specific contr...

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Neutralization Serotyping of BK Polyomavirus Infection in Kidney Transplant Recipients

BK polyomavirus (BKV or BKPyV) associated nephropathy affects up to 10% of kidney transplant recipients (KTRs). BKV isolates are categorized into four genotypes. It is currently unclear whether the four genotypes are also serotypes. To address this issue, we developed high-throughput serological assays based on antibody-mediated neutralization of BKV genotype I and IV reporter vectors (pseudovi...

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BK Virus and Nephropathy in Kidney Transplant Recipients

Polyomavirus-associated nephropathy (PVAN) remains an important cause of allograft dysfunction and graft loss after kidney transplantation [1, 2]. Furthermore, up to 10% of renal transplant recipients show a viral reactivation that can lead to PVAN and delayed treatment results in high risk of graft loss (up to 80%) [3]. We read with interest the article published by Pakfetrat, et al [2], and w...

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[BK virus infections in pediatric kidney transplant recipients].

Primary BK virus (BKV) infections acquired mainly during childhood are usually asymptomatic. Several studies revealed its seroprevalence in adult population as high as 90% worldwide. Following primary infection, virus persists as latent infection in the urogenital tract. In renal transplant recipients, primary infection and reactivations affect 10% of patients and without treatment, more than h...

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ژورنال

عنوان ژورنال: Kidney International Reports

سال: 2020

ISSN: 2468-0249

DOI: 10.1016/j.ekir.2020.02.886